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Antipsychotics

1.1 Class members

Antipsychotic

Category

Formulations

Strengths

Amisulpride

Second-generation; substituted benzamide

Tablets

50 mg, 100 mg, 200 mg, 400 mg

Oral solution

100 mg/ml

Aripiprazole

Second-generation; dihydrocarbostyril

Tablets

5 mg, 10 mg, 15 mg, 30 mg

Oral solution

1 mg/ml

Injection

9.75 mg/1.3 ml

Asenapine1

Second-generation; dibenzo-oxepino pyrrole

Sublingual tablets

5 mg, 10 mg

Benperidol2

First-generation; butyrophenone

Tablets

250 micrograms

Chlorpromazine hydrochloride

First-generation; phenothiazine

Tablets

25 mg, 50 mg, 100 mg

Oral solution

25 mg/5ml, 100 mg/5 ml

Injection

25 mg/ml: 1 ml, 2 ml

Clozapine

Second-generation; dibenzodiazepine derivative

Tablets

25 mg, 50 mg, 100 mg, 200 mg

Oral suspension

50 mg/ml

Flupentixol

First-generation; thioxanthene

Tablets

3 mg

Flupentixol decanoate

First-generation; thioxanthene

Prolonged-release injection

20 mg/ml: 1 ml, 2 ml
100 mg/ml: 0.5 ml, 1 ml
200 mg/ml: 1 ml

Fluphenazine decanoate

First-generation; phenothiazine

Prolonged-release injection

25 mg/ml: 0.5 ml, 1 ml, 2 ml
100 mg/ml: 0.5 ml, 1 ml

Haloperidol

First-generation; butyrophenone

Capsules

500 micrograms

Tablets

500 micrograms, 1.5 mg, 5 mg, 10 mg, 20 mg

Oral liquid

1 mg/ml, 2 mg/ml

Injection

5 mg/ml: 1 ml

Prolonged-release injection

50 mg/ml: 1 ml

100 mg/ml: 1 ml

Levomepromazine

First-generation<>; phenothiazine

Tablets

25 mg

Injection

25 mg/ml: 1 ml

Olanzapine

Second-generation; thienobenzodiazepine

Tablets

2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg

Orodispersible tablets

5 mg, 10 mg, 15 mg, 20 mg

Injection

5 mg/ml: 10 ml

Olanzapine embonate

Second-generation; thienobenzodiazepine

Prolonged-release injection

210 mg, 300 mg, 405 mg

Paliperidone

Second-generation; benzisoxazole derivative; active metabolite of risperidone

Tablets

3 mg, 6 mg, 9 mg

Prolonged-release injection

50 mg, 75 mg, 100 mg, 150 mg

Pericyazine

First-generation; phenothiazine

Tablets

2.5 mg, 10 mg

Oral solution

10 mg/5 ml

Perphenazine

First-generation; phenothiazine

Tablets

2 mg, 4 mg

Pimozide

First-generation; diphenylbutylpiperidine

Tablets

4 mg

Pipotiazine palmitate

First-generation; phenothiazine

Prolonged-release injection

50 mg/ml: 1 ml, 2 ml

Prochlorperazine

First-generation; phenothiazine

Tablets

5 mg

Oral solution

5 mg/5 ml

Injection

12.5 mg/ml: 1 ml

Promazine3

First-generation; phenothiazine

Tablets

25 mg, 50 mg

Quetiapine

Second-generation; dibenzothiazepine

Tablets

25 mg, 100 mg, 150 mg, 200 mg, 300 mg

Prolonged-release tablets

50 mg, 150 mg, 200 mg, 300 mg, 400 mg

Risperidone

Second-generation; benzisoxazole

Tablets

500 micrograms, 1 mg, 2 mg, 3 mg, 4 mg, 6 mg

Orodispersible tablets

500 micrograms, 1 mg, 2 mg, 3 mg, 4 mg

Oral liquid

1 mg/ml

Prolonged-release injection

25 mg, 37.5 mg, 50 mg

Sulpiride

First-generation; substituted benzamide

Tablets

200 mg, 400 mg

Oral solution

200 mg/5 ml

Trifluoperazine

First-generation; phenothiazine

Tablets

1 mg, 5 mg

Oral solution

1 mg/5 ml, 5 mg/5 ml

Zuclopenthixol

First-generation; thioxanthene

Tablets

2 mg, 10 mg, 25 mg

Zuclopenthixol acetate

First-generation thioxanthene

Injection

50 mg/ml: 1 ml, 2 ml

Zuclopenthixol decanoate

First-generation thioxanthene

Prolonged-release injection

200 mg/ml: 1 ml
500 mg/ml: 1 ml


  1. Licensed only for the treatment of moderate to severe manic episodes associated with bipolar I disorders
  2. Licensed only for the control of deviant anti-social sexual behaviour (hyperprolactinaemic effect)
  3. Licensed only as an adjunct to short-term management of moderate to severe psychomotor agitation and for agitation and restlessness in the elderly