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6. Further information

British National Formulary—available online

Martindale: the complete drug reference—available online

NICE. Schizophrenia: Core interventions in the treatment and management of schizophrenia in adults in primary and secondary care – clinical guideline 82 (issued March 2009)

Barnes TRE, et al. Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology. J Psychopharmacol 2011; 25: 567–620

Information from MHRA

Note. References to older MHRA1 advice is included for background only; the information will have been incorporated into summaries of product characteristics and some will have been superseded.


Article title


Drug Safety Update September 2011

Antipsychotics: use during third trimester of pregnancy and extrapyramidal effects or withdrawal symptoms in newborns

Risk of extrapyramidal effects and withdrawal effects in newborns born to mothers on antipsychotics during the third trimester

Drug Safety Update April 2011

Atypical (second-generation) antipsychotics: reminder to monitor and manage weight, glucose, and lipid levels

MHRA website March 2010

Antipsychotic drugs

Uses of antipsychotics, mechanism of action, side-effects and use in elderly people with dementia

Drug Safety Update June 2009

Antipsychotics: risk of venous thromboembolic events

Before and during treatment with antipsychotics, risk factors for venous thromboembolism should be identified and addressed

Drug Safety Update March 2009

Antipsychotics: use in elderly people with dementia

Antipsychotics may increase risk of stroke and slightly increase risk of early death in the elderly

Pharmacovigilance Working Party assessment report

Antipsychotics and cerebrovascular accident

Basis for the introduction of warning on cardiovascular adverse events into summaries of product characteristics

  1. Medicines and Healthcare products Regulatory Agency, the government body which regulates many aspects of the testing, manufacture, supply, and use of medicines and medical devices