2. Class members and licensed uses
Consult the summary of product characteristics for details of authorised indications of each SSRI.
SSRIs: Approved names, common proprietary names and licensed indications
Citalopram |
Escital-opram
|
Fluoxetine |
Fluvoxamine |
Paroxetine |
Sertraline |
|
---|---|---|---|---|---|---|
Common proprietory names |
Cipramil |
Cipralex |
Prozac |
Faverin |
Seroxat |
Lustral |
Depressive illness 2 |
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Generalised anxiety disorder |
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Obsessive–compulsive disorder |
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Panic disorder with or without agoraphobia 3 |
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Social anxiety disorder (social phobia) |
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Post-traumatic stress disorder |
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Bulimia nervosa |
Antidepressants in other classes may also inhibit reuptake of serotonin, but only SSRIs are discussed here.
Only the following SSRIs are licensed for children and adolescents:
- Fluoxetine for the treatment of moderate to severe major depressive episode (in combination with psychological therapy) in children aged over eight years and adolescents
- Fluvoxamine for the treatment of obsessive–compulsive disorder in children aged over eight years and adolescents
- Sertraline for the treatment of obsessive–compulsive disorder in children aged over six years and adolescents.
- An enantiomer is one of a pair of chemical molecules with identical molecular formula, but one enantiomer cannot be superimposed on the other because it is a mirror image of the other. Often one enantiomer exerts considerably more biological activity than the other.↩
- A psychiatric disorder characterised by lowered mood, reduced energy and decreased activity. The severity of a depressive episode is divided clinically into mild, moderate and severe subtypes (the latter may or may not have psychotic features). Repeated episodes of depression, without a history of mania, are classified as recurrent depressive disorder.↩
- Abnormal fear or anxiety induced by being in crowds or in open spaces—environments which seem difficult to escape from or obtain help.↩